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diagnosis differential algorithm injury acute aki nephrology rheumatology classification compared comparison dermatology dka erythemas generalized glomerulonephritis hepatitis hepatology infusion ivfluids
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... #AKI #Acute #Kidney ... Diagnosis #nephrology #causes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... • Limited to Kidney ... : Anti-GBM Glomerulonephritis ... involvement: Anti-GBM ... Glomerulonephritis #Vasculitis
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... tubular necrosis (causes ... : sepsis, meds, ... #AKI #Acute #Kidney
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... glomerulonephritis) • Anti-GBM ... Polyarteritis Nodosa: - Kidneys ... mucositis - Rash ... Kidneys -> glomerulonephritis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... Glomerulonephritis / Vasculits ... ANCA, ANA, Anti-GBM ... imaging #Acute #Kidney
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Infectious: Influenza, EBV ... Bacteremia, Sepsis • Kidneys ... PMR, RA, SLE, Vasculitis ... Differential #Diagnosis #causes
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... potential inciting causes ... Haverhill fever caused ... Rash is usually ... of necrotizing vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... musculoskeletal systems • Kidneys ... , mucositis • Rash ... tract, and often causes ... pain and GN Anti-GBM
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... HBV, HCV, HEV, EBV ... disease: > 2 • NASH ... cardiac muscle, RBC, kidney ... cardiac muscle, kidneys
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis - Kupperman et al. NEJM 2018 https://www.nejm.org/doi/full/10.1056/NEJMoa1716816 Study
NEJM 2018 https ... out what does cause ... TessaRDavis #EBM ... VisualAbstract #Peds ... Infusion #Rates #NEJM
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