33 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... life-threatening • Treatment ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... months to years) Systemic ... #comparison #table ... diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... ) Clinical Manifestations ... autoantibodies that will cause ... #management #treatment
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
characterized by a systemic ... , but without treatment ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... erythematosus [SLE ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... solid cancers • Systemic ... #management #treatment ... #rheumatology
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
In primary systemic ... well-recognized cause ... and treatment are ... #photo #AL #lightchain ... #NEJM
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... (cutaneous or systemic ... multiforme • Acute systemic ... Erythemas #comparison #table ... #differential #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... extensive skin rash ... Edema in 70% of cases ... disease: symptomatic treatment ... #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... in literature (NEJM ... (Cornelia NEJM ... Treatment of GCA ... #Management