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diagnosis rheumatology neurology sle systemic nephrology activation antinxp2 antinxp2dm barre cerebritis classification cns comparison cryoglobulinemia cryoglobulins dermatology dermatomyositis differential druginduced
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease Treatment ... #Erythematosus ... #rheumatology #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... life-threatening • Treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... Erythematosus ( ... 40, F:M 9:1 • Clinical
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
Summary CLINICAL ... • Nephritic syndrome ... (Casts) • Marked ... • Vasculitic rash ... deposits common TREATMENT
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... Petechial or purpuric rash ... erythematosus [ ... Treatment: • Corticosteroids ... #Diagnosis #Management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • They can cause ... : • Clinical triad ... (e.g. systemic lupus ... erythematosus (
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Muscle Toxicity - Summary ... Clinical Presentation ... GBS), systemic lupus ... erythematosus ( ... myopathy #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Associated with: ... Clinical Picture ... Clinical DX: - ... immunosuppressants - Meds ... Gravis #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... Summary Causes ... Dermatomyositis Clinical ... Heme associated ... #causes #treatment
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