17 results
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Rash Secondary ... with or without treatment ... , but without treatment ... resembling rashes caused ... Clinical #Photo #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
transplantation Secondary ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... thrombosis and/or blood-brain ... cerebritis #diagnosis #management ... #treatment
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... normal in mild cases ... Avoid meds that ... #treatment #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... : symptomatic treatment ... • Severe disease ... DRESS #Syndrome #dermatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full Blood ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Causes: - Idiopathic ... neutrophils in the blood ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... donors (due to anti-HLA ... Transfusion #diagnosis #management ... #hematology #reactions