13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... #CNS #neurology ... #diagnosis #management
Pediatric Vomiting - Gastrointestinal and Systemic Causes - Differential Diagnosis Algorithm
Hepatobiliary:
 • Acute Hepatitis
 • Acute
Pediatric Vomiting ... Causes - Differential ... Diagnosis Algorithm ... Intracranial Pressure (CNS ... #Peds #Pediatrics
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Manifestations: Malar rash ... : Chronic disease ... #lupus #Systemic
Causes of Hypotonic Infant (Floppy Newborn) - Differential Diagnosis Algorithm
Central Nervous System - Decreased LOC, Axial
Causes of Hypotonic ... - Differential Diagnosis ... Central Nervous System ... Hemorrhage • CNS ... #Peds #Pediatrics
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
ophthalmoplegia), systemic ... signs (rash, swelling ... sarcoid or other CNS ... inflammatory cause ... #Neurology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... months to years) Systemic ... : Chronic disease ... #rheumatology #diagnosis ... #management
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... suspicion of severe disease ... guidelines General - Systemic ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(CNS) dysfunction ... Petechial or purpuric rash ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Parotid swelling CNS ... • 8%-27% for CNS ... #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... as SLE, atherosclerotic ... , mucositis • Rash ... tract, and often causes ... chorioretinitis, CNS