12 results
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... Treatment: 1 ... Amyl nitrite - causes ... #Toxicology #Pathophysiology ... #Management #Treatment
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
is a treatment ... for severe toxicity ... life-threatening toxicity ... #Therapy #Toxicology ... #Management #Pharmacology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... altered 2) You see ... no respiratory cause ... #Toxicology #diagnosis ... #management #Treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... constitutional symptoms • Treatment ... Manifestations: Malar rash ... life-threatening • Treatment ... Usual therapeutic management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... Usual therapeutic management
Carbon Monoxide Poisoning

Symptoms are non-specific:
 - Headache 90%
 - Nausea/vomiting 50%
 - Vertigo 50%
 - Altered
Headache 90% - Nausea ... affected (inc pets ... Treatment: 100% ... Monoxide #Poisoning #Toxicology ... #diagnosis #management
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Sedation Scale (RASS ... it should not cause ... dissociative drug, it causes ... glycol (solvent) toxicity ... CriticalCare #diagnosis #management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... Exclude other causes ... macrophages Treatment ... Pulmonary #diagnosis #management ... #Toxicology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... muscles: “myasthenic crises ... Myasthenia Crises ... immunosuppressants - Meds ... Gravis #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Medication/Drug toxicity ... the underlying cause ... • Treatment of ... until cause identified ... Syndrome #diagnosis #management