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differential lupus management erythematosus signs systemic dermatology hematology oncology pathophysiology pulmonary ana anca antibodies antibody antineutrophil antinuclear autoimmune classification complications
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Differential Diagnosis ... Water - Pus - Blood ... Vasculature: - PE ... Pulmonary HTN - Vasculitis ... Hepatopulmonary syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... Presentation - Systemic Symptoms ... , and SLE) • Urinalysis ... #rheumatology #
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... • Sjögren syndrome ... vasculitis - MPO ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis ... #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... • Goodpasture syndrome ... (inflamed blood ... #diagnosis #rheumatology
SOAP BRAIN MD Mnemonic for Systemic Lupus Erythematosus (SLE) S - Serositis (Pleuritis, Pericarditis) O - Oral Ulcers A
Photosensitivity B - Blood ... Pancytopenia) R - Renal ... Neuropsychiatric Symptoms ... #Rheumatology # ... Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... pulses, bruits, or blood ... , mucositis • Rash ... tract, and often causes ... #Rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
endothelial lining of blood ... periumbilical region), nausea ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis ... #Signs #Symptoms
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