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diagnosis lupus sle erythematosus hematology neurology syndrome activation arteritis bells cell cerebritis coagulation comparison dic disseminated druginduced fungal gca giantcell
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... life-threatening • Treatment ... #Summary #rheumatology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
- Atypical Clinical ... ophthalmoplegia), systemic ... signs (rash, swelling ... inflammatory cause ... #Treatment #Neurology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(CNS) dysfunction ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... months to years) Systemic ... comparison #table #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... (Cornelia NEJM ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... Thromboembolism (7%) • CNS ... #treatment #management ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... • Major blood ... especially the CNS ... MC: CNS CSF: • ... Fungal #Diagnosis #Management
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
populations) CLINICAL ... CNS involvement: ... Laboratory Tests: Blood ... TREATMENT OPTIONS ... Histiocytosis #Diagnosis #Management
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