22 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
: Fever (50%), Depression ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... #signs #symptoms
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Differential Diagnosis Algorithm ... GI, lung, skin), ... B-cell lymphomas), Systemic ... Aspergillus), Viral (HIV ... , Sarcoidosis, SLE
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
in HIV - Differential ... Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... Constitutional symptoms ... , rales, interstitial
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... (45%) • Fever ... (28%) • Skin rash ... Central nervous system ... • New onset SLE
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... autoantibodies #signs #symptoms
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... history of cancer, HIV ... pupil (AACG) • Systemic ... symptoms and signs ... (e.g., fever, myalgia
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... Symptoms (DRESS ... extensive skin rash ... Fever >38.5 2. ... SinaiBmoreIMRes #DRESS #Syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... Induced Lupus: • Symptoms ... to: Arthritis, Fever ... #Systemic #Lupus
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... the lymphatic system ... General: fever, ... 5-10%, nervous system ... : ACUTE, fever,