21 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
: Fever (50%), Depression ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... #signs #symptoms
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Algorithm Idiopathic ... GI, lung, skin), ... B-cell lymphomas), Systemic ... Aspergillus), Viral (HIV ... , Sarcoidosis, SLE
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... arthritis - (Reiter’s syndrome ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... autoantibodies #signs #symptoms
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
(45%) • Fever ... (28%) • Skin rash ... Central nervous system ... • New onset SLE ... #HIV #diagnosis
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Diagnosis Framework ... Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... Constitutional symptoms ... #differential #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
- Nonremitting fever ... Petechial or purpuric rash ... ) • Heart, lung ... erythematosus [SLE ... #Diagnosis #Management
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... history of cancer, HIV ... pupil (AACG) • Systemic ... symptoms and signs ... (e.g., fever, myalgia
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... Symptoms (DRESS ... Symptoms: • The ... Fever >38.5 2. ... SinaiBmoreIMRes #DRESS #Syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... Differential Diagnosis ... Induced Lupus: • Symptoms ... to: Arthritis, Fever