12 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Fever (50%), Depression ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... erythematosus #signs #symptoms
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #dermatology #joint
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... : • Joint pain ... : • Symptoms limited ... to: Arthritis, Fever
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... Lupusreference #SLE ... autoantibodies #signs #symptoms
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... inflammation of the joints ... and pain of the joints ... - Lupus - Leukemia
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... General: fever, ... skin (16-32%): lupus ... : ACUTE, fever, ... presentation with fever
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... Petechial or purpuric rash ... ) • Heart, lung ... SJIA], systemic lupus ... erythematosus [SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... , mucositis • Rash ... • Progressive symptoms ... Palpable purpura, joint