15 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
) General: Fever ... effusion, Restrictive lung ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... can present with rash ... anti-synthetase syndrome ... Can also see mechanics
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Common Causes: • Autoimmune ... Adrenals: • Lung ... pseudomonas) Autoimmune ... • Low-grade fever ... adrenalitis cases
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... formation, systemic autoimmune ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... disease • Non-autoimmune ... deficiencies • Autoimmune ... Induced Lupus: • Symptoms ... to: Arthritis, Fever
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... autoantibodies #signs ... #symptoms #mimickers
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Pneumonia: • 3 syndromes ... • CT: Halo sign ... of a "flu-like syndrome ... Constitutional symptoms ... , rales, interstitial
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... Predisposing conditions: Autoimmune ... (SLE/APLS), Malignancy ... #Endocarditis #comparison
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... General: fever, ... : ACUTE, fever, ... presentation with fever ... Diagnosis #Management #Signs
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... run-down or tired • Fevers ... Nasal polyps and signs ... in the adjacent lung ... of the affected lung