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diagnosis differential rheumatology erythematosus lupus systemic infectiousdiseases neurology pulmonary aids autoantibodies autoimmune bronchiectasis cardiology classification cord disorders endocarditis infections management
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... , Vasculitis, Purpura ... effusion, Restrictive lung ... erythematosus #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Rash, arthritis ... Presentation - Systemic Symptoms ... purpura: strong sign ... , and SLE) • Urinalysis ... Cryoglobulins • HIV
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... anemia 4% - Myositis ... 4% - Lung involvement ... autoantibodies #signs
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Pneumonia: • 3 syndromes ... • CT: Halo sign ... of a "flu-like syndrome ... Constitutional symptoms ... , rales, interstitial
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... • Transverse Myelitis ... Induced Lupus: • Symptoms ... to: Arthritis, Fever ... and leukemia • Lung
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Rash, arthritis ... • Progressive symptoms
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... simplex virus, HIV ... Disorders: - SLE ... - Sjogren - Vasculitis
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... , HIV, CMV, HTLV ... Behcet disease - SLE ... MCTD, Sjogren syndrome ... differential #algorithm
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... run-down or tired • Fevers ... Nasal polyps and signs ... in the adjacent lung ... , CCP, ANCA • HIV
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... : Fever, joint pain ... : • Fever • Interstitial
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