9 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Syndrome and Acute ... child * Severe cases ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Non-lmmune: • HELLP ... Syndrome • TTP ... #Causes #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Syndrome (Hemolysis ... features: Hemolysis, Thrombocytopenia ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #AFLP
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
- THE ALGORITHMIC ... approach can help ... petechial or purpuric rash ... #Diagnosis #Dermatology ... Purpural #Purpuric #Rash
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... vein: Budd-chiari syndrome ... • Pregnancy: HELLP ... • Gilbert's syndrome ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
(Alk phos/ULN ALP ... to synthesis - rises ... disease: > 2 • NASH ... • Gilbert's syndrome ... #differential #Hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Petechial or purpuric rash ... leukopenia, anemia, and thrombocytopenia ... Diagnosis #Management #Hematology ... #Rheumatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... at that stage rather ... presence of metabolic syndrome ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver