16 results
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
1) heliotrope rash ... shawl sign, and 3) Gottron's ... HeliotropeRash #Gottrons ... #Papules #Clinical ... #Photo
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Rheumatic fever Gottron's ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Gottron's Papules in Dermatomyositis

Another classic clue is Gottron's papules which are small grouped flat topped papules
in Dermatomyositis ... #Papules #Rash ... #Dermatomyositis ... #Dermatology #Clinical ... #Photo #Hands #
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... Dermatomyositis ... can present with rash ... including heliotrope rash ... holster sign, and Gottron's
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... papules • Inverse Gottron ... auricular papules Clinical ... #rheumatology #
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... muscle weakness, rash ... uncommon 5-15% of lupus ... differential #diagnosis #comparison ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... #sle #comparison ... #table #rheumatology
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
with heliotrope rash ... shawl sign, and Gottron's ... 1) heliotrope rash ... #dermatology #clinical ... #photo
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... Pathogenesis and clinical ... red papules -> Gottron ... -> Heliotrope Rash ... Pathophysiology #Signs #Symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... erythematosus #signs #symptoms ... #diagnosis #rheumatology