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diagnosis erythematosus systemic differential vasculitis autoantibodies classification complications druginduced management manifestations mimickers mucocutaneous pathophysiology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Signs/Symptoms ... , Fever, Malar rash ... , Oral ulcers, Rash ... #Signs #Symptoms ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... #sle #comparison ... #table #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... #symptoms #complications
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... Photosensitivity • Malar rash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Presentation - Systemic Symptoms ... purpura: strong sign ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... , mucositis • Rash ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
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