9 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... #Classification ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... cell antigens, leading ... to complement activation ... #allergy #table ... #classification
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... nervous system (CNS) dysfunction ... MAS #Macrophage #Activation ... Diagnosis #Management #Hematology
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... • Most common type ... #Types #diagnosis ... warm #wet #dry #table
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... degranulation, leading ... immune reaction, leading ... because T-Cell activation ... #Classification
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
sympathetic + ADH activation ... Classification: ... HRS-AKI (formerly Type ... HRS-Non-AKI (formerly Type ... Hepatorenal #Syndrome #Hepatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Malignancy (e.g. hematologic ... Kikuchi disease • Type-I ... mild cognitive dysfunction ... Chronic B-cell activation
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... Types of HLH • ... MAS-HLH: Macrophage Activation ... uncontrolled immune activation ... Diagnosis #Management #Hematology
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
meet criteria for hematologic ... or evolve into hematologic ... guide subtype classification ... Complement pathway activation ... vasculitis Types