16 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... #Classification ... #Pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... Allergen-specific lgE causes ... cell antigens, leading ... to complement activation ... allergy #table #classification
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... exposure to allergen causes ... because T-Cell activation ... ivy) #TypeIV #Type4 ... Allergy #Immunology #pathophysiology
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
gets activated leading ... skin, and brain leading ... by endothelial activation ... Exposure of Type-IV ... Rheumatic #Fever #Pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
blood vessels, leading ... oxide release - Activation ... Edema #Medication #Causes ... #Pharmacology #Pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
channels open leading ... Vaughan Williams Classification ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... : CLASS 1 - Sodium ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... cell surfaces causes ... exposure to allergen causes ... because T-Cell activation ... #Classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... sympathetic + ADH activation ... Classification: ... HRS-AKI (formerly Type ... HRS-Non-AKI (formerly Type