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Calculating a Reticulocyte Index (RI) Reticulocyte Index = Absolute Reticulocyte Count / Maturation Correction Absolute Reticulocyte Count =
Calculating a Reticulocyte ... Index (RI) Reticulocyte ... Index = Absolute Reticulocyte ... Count = % of reticulocytes ... hematology #diagnosis #anemia
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Reticulocyte count ... Corrected reticulocyte ... for degree of anemia ... thecurbsiders podcast #Anemia
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... bilirubin • ↑ Reticulocytes ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
peripheral smear, reticulocyte ... Production (↓ reticulocytes ... (hemolysis, ↑ reticulocytes
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... peripheral smear, a reticulocyte ... elevated, but anemia ... elevation in the reticulocyte ... megaloblastic anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... of: Decreased Reticulocytes ... Normal / Decreased Reticulocytes ... • Anemia of Chronic ... Destruction - Increased Reticulocytes
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Reticulocyte Production ... days) it takes a reticulocyte ... particular degree of anemia ... Index < 2: • Anemia ... EricsMedicalLectures/ #Reticulocyte
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms Anemia ... symptoms related to anemia ... i.e., corrected reticulocyte ... i.e., corrected reticulocyte ... #Pancytopenia #reticulocytes
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... Extravascular Hemolysis Reticulocytes ... #Hemolytic #Anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Sideroblastic anemia ... Megaloblastic anemia ... syndrome, Increased reticulocyte ... , Pernicious anemia
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