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Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... labs: CBC, BMP, Reticulocytes ... schistocytes > 1% • ↑ Reticulocyte ... index • ↑ LDH ... Microangiopathy #TMA #Differential
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Reticulocyte Production ... Index = (Retic ... days) it takes a reticulocyte ... EricsMedicalLectures/ #Reticulocyte ... hematology #anemia #differential
Calculating a Reticulocyte Index (RI) Reticulocyte Index = Absolute Reticulocyte Count / Maturation Correction Absolute Reticulocyte Count =
Calculating a Reticulocyte ... Index (RI) Reticulocyte ... Index = Absolute ... Reticulocyte Count ... #Index #RI #RPI
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Pancytopenia - Differential ... peripheral smear, reticulocyte ... Production (↓ reticulocytes ... (hemolysis, ↑ reticulocytes ... #Pancytopenia #Differential
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Reticulocyte count ... percentage of reticulocytes ... Corrected reticulocyte ... count OR reticulocyte ... index above 2%
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
peripheral smear, a reticulocyte ... specifically order a reticulocyte ... index in some laboratories ... likely cause if the reticulocyte ... elevation in the reticulocyte
Isolated Hyperbilirubinemia - Differential Diagnosis Algorithm Direct Hyperbilirubinemia: Dubin-Johnson Syndrome, Rotor Syndrome Indirect Hyperbilirubinemia: - Trauma, Hematoma,
Hyperbilirubinemia - Differential ... , Haptoglobin, Reticulocyte ... , Haptoglobin, Reticulocyte ... Hyperbilirubinemia #Isolated #Differential
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... of: Decreased Reticulocytes ... Normal / Decreased Reticulocytes ... Destruction - Increased Reticulocytes ... Classification #Approach #Differential
Polychromatophilia - Note 2 large blue-gray erythrocytes as seen on H&E stain. On a stain for
On a stain for reticulocytes ... The reticulocyte
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
., corrected reticulocyte ... i.e., corrected reticulocyte ... indicates IDA Mentzer index ... #Pancytopenia #reticulocytes
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