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Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
ALP enzyme- Discovered ... in 1923 Low ALP ... Most cases diagnosed ... teeth • Muscular/Rheum ... Phosphatase: • Other causes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
phos/ULN ALP) ... Cholestasis • ALP ... disease • If ALP ... both are normal - ALP ... • Elevation of ALP
Drugs Causing Acute Pancreatitis Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... of AP are ruled ... out other common causes ... Class II: Cases ... #Pancreatitis #Causes
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Polyneuropathy, ALS ... • Inflammatory/Rheum ... Differential #Diagnosis #causes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
or AST > ALP): ... • Severe - ALT ... • Moderate - ALT ... Cholestatic Pattern (ALP ... > ALT or AST):
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
kidney, brain ALT ... for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP)
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
Diagnosis #IM #Rheum
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... specificity to elevated ALP ... • AST/ALT > ALP ... GGT/5-NT: ↑ - ALP ... hemolysis) • ALP
Identifying, referring and managing spondyloarthritis #Management #PrimaryCare #Rheum #Spondyloarthritis #BMJ
#PrimaryCare #Rheum
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Enzymes (LFTs) - Causes ... Injury • AST/ALT ... elevation > Alk ... phos • ALT more ... • R value = (ALT
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