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diagnosis management differential aids causes hematology hiv oncology syndromes apml associated barre cauda caudaequina chagas cns dementia differentiation disease disorder
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Antimicrobial treatment ... status, and focal neurologic ... confusion, and focal neurologic ... opportunistic #InfectiousDiseases ... #Neurology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... 4 weeks after starting ... and not direct infection ... due to increased CSF ... differential #TB #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Transplantation including bone ... Neurological symptoms ... Diagnosis: • Infection ... epilepticus Treatment
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... surgery, trauma, and bone-marrow ... than one after symptom ... and cauda equina TREATMENT ... diagnosis #management #neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... Differential Diagnosis: Infection ... sepsis), PE, DAH, CHF
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... toon • Spinal infection ... axial T1 and T2 Treatment ... diagnosis #causes #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... petechiae) • Frequent infections ... • Parvovirus infection ... factor (GCSF) treatments ... factors (examples: G-CSF
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
Without treatment ... and nephrotic syndrome ... exposure to or symptoms ... granuIomas on skin, bone ... Tertiary #Diagnosis #Staging
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Toxins - Drugs - Statins ... - ETOH - Infection ... : • Triad of symptoms ... urine • Other symptoms ... #nephrology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
early stages of infection ... • Depressive symptoms ... : • Increased CSF ... The clinical syndrome ... dementia #AIDS #Neurology
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