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clinical ucsdh dermatology diagnosis skinrash differential management ophthalmology skin syndrome dermatomyositis pharmacology physicalexam treatment algorithm diabetes endocrinology infection nejm nephrology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
injection • Semaglutide ... dulaglutide, and semaglutide ... e.g. diarrhea, nausea ... not definitively cause ... Pharmacology #Summary #DM2
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
Weekly Ozempic (Semaglutide ... being studied (semaglutide ... Dosing #Diabetes #DM2
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
agent • Does not cause ... mL/minute/1.73 rm2 ... mL/minute/1.73 m2 ... e.g. diarrhea, nausea ... Pharmacology #Summary #DM2
Terry's Nails Proximal paleness extending halfway up the nail, often eliminating the lunula. Darker distal band. Seen
cirrhosis, CHF, DM2 ... PhysicalExam #Clinical #Photo
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm Lifestyle Modifications (Diet and Exercise) -> Start
relative with DM2 ... associated with DM ... • Secondary Causes ... Management #algorithm #DM2
Sebaceous hyperplasia - Yellow papule - Donut-shape - Central umbilication - Telangiectasia
Usually multiple - Causes ... Benign #Clinical #Photo
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Decrease #Diagnosis #DM2
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
Secondary Causes ... 90 (>130/80 for DM ... end-organ damage or DM ... withdrawal Anatomic Causes ... RAS Metabolic Causes
Molluscum: Numerous papules caused by viral infection. Charlie Goldberg, M.D. - UCSD Catalog of Clinical Images #Clinical #Photo
Numerous papules caused ... Images #Clinical #Photo
Conjunctival Petechiae: Conjunctival petechiae, in this case secondary to endocarditis. Photo credit, Josh Fierer, M.D. Charlie Goldberg, M.D.
petechiae, in this case ... Photo credit, Josh ... Images #Clinical #Photo
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