58 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... anti-synthetase syndrome ... /full triad at diagnosis ... #diagnosis #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
SHARP - Lupus Diagnosis ... D Discoid Rash ... Antibody (ANA) M Mucositis ... Pleuritis) H Hematologic ... #diagnosis #mnemonic
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome ... Inclusion Body Myositis ... Idiopathic #Myopathy #Comparison ... Managment #algorithm #Rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... muscle weakness, rash ... Inclusion Body Myositis ... #differential #diagnosis ... #comparison #rheumatology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Anti-Synthetase Syndrome ... Inclusion Body Myositis ... MSAs #clinical #diagnosis ... #rheumatology #
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
the ED with a rash ... the patient’s rash ... Scalded #Skin #Syndrome ... SSSS #Clinical #Photo ... Peds #Pediatrics #Dermatology
Yao Syndrome vs VEXAS

Zhuoer Xie, MD @ZhuoerXie

#Yao #Syndrome #VEXAS #diagnosis #comparison #rheumatology
Yao Syndrome vs ... ZhuoerXie #Yao #Syndrome ... #VEXAS #diagnosis ... #comparison #rheumatology
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Differential Diagnosis ... , DRESS, Sweet syndrome ... SCVMCMed #Fever #Rash ... #dermatology
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
Christmas Tree Rash ... - Differential diagnosis ... ChristmasTree #Rash ... rosea #clinical #dermatology ... #photo #PhysicalExam
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... Demyelinating syndromes ... Glomerulonephritis Myositis ... signs #symptoms #diagnosis ... #rheumatology