15 results
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential Diagnosis ... valves, COPD, ILD ... , OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... #causes #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... Clinical Presentation ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Ischemic Liver, IBD ... coagulation and other causes ... Vasculitis • Injury ... Venous #Arterial #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #rheumatology # ... cerebritis #diagnosis
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
the most common cause ... Pathophysiology: ... #Agraphia #clinical ... #neurology #diagnosis ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... cytokines (TNFa,lL1, IL6 ... accumulation of clinical ... Assessment • Clinical ... treatment #summary #rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... the critically ill ... liver or renal injury ... 30mmHg) - Severe anemia ... gluconeogenesis Liver Injury
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... poor nutrition Clinical ... breath, wasting, anemia ... Loss of teeth Anemia ... , or any other cause
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis (SRC) Clinical ... microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... the Journal of Clinical ... reasoning during clinical ... #pathophysiology ... #differential #diagnosis