41 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... Proliferative Class Ill ... Classification #Classes ... #differential #diagnosis ... #management #nephrology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... Discontinuation of causal ... #rheumatology #diagnosis ... #management
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
caustic mucosal injury ... Abdominal pain, nausea ... post-ingestion) - Symptom ... #Toxicology #Diagnosis ... #Management #Ferrous
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... - Summary Clinical ... GBS), systemic lupus ... Direct muscle injury ... #management #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Summary Causes ... Dermatomyositis Clinical ... #Management #causes ... #treatment #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #management #treatment
Hordeolum vs Chalazion

Hordeolum (Stye):
 • Location: Most commonly found at or near an eyelash follicle
 •
eyelash follicle • Cause ... eyelashes on the upper lid ... • Cause: A blocked ... eyedrops, surgery #Clinical ... #Diagnosis #Management
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
and acute kidney injury ... presentation - Clinical ... also includes symptoms ... LacticAcidosis #Toxicity ... #Management
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... , ranging from mild ... disorders (Systemic lupus ... Manifestations #diagnosis ... #neurology #symptoms
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
cytotoxic lung injury ... gradually with symptoms ... Exclusion of other ILDs ... Improvement in symptoms ... #management #Toxicology