15 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Involvement in Systemic Lupus ... Renal #diseases #SLE ... #Systemic #Lupus ... Erythematosus #venn #nephrology ... #nephritis #classification
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... Induction Rx: high-dose ... Erythematosus #SLE ... #CNS #neurology
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus ... #Nephritis #SLE ... #Classification ... diagnosis #management #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and a high ... Skin Disease Classification ... • May involve PNS ... and CNS • Headache
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... #rheumatology #nephrology
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... treat non-renal SLE ... treat extra-renal SLE ... therapy (MMF plus CNI ... Treatment #management #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Sodium >145 mmol/L High ... Osmotic diuresis (see ... 300 mmol/kg • Diabetes ... Hypernatremia #Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... (Uncontrolled diabetes ... insufficiency/Failure • SLE ... causes #potassium #high ... #nephrology
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
MINIMIZE INs: ... TO PO • USE HIGH ... diuresis, address diuretic ... especially in high ... Early nephrologv
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
0.8 Normal + High ... 0.8-2.0 Pure High ... Ketoacidosis (starvation, diabetic ... acidosis: - CNS ... Diagnosis #Summary #Nephrology