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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Erythematosus #SLE ... #hematology #rheumatology ... #differential # ... diagnosis #causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... Induction Rx: high-dose ... APS), Secondary ... #CNS #neurology
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
#Nephritis #SLE ... Classification #Classes ... #differential # ... diagnosis #management ... #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential ... #Diagnosis #Causes ... #nephrology #sodium ... #high
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Diagnosis Algorithm ... Bullous systemic lupus ... tarda • Diabetic ... Vesiculobullous #SkinRash #dermatology ... #causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential ... Diagnosis Algorithm ... suggests either secondary ... Ureterosigmoidostomy, Diabetic ... #causes #nephrology
Causes of Dilated Cardiomyopathy DCMP - Differential Diagnosis Algorithm
Idiopathic DCMP: Viral, Inflammatory cardiomyopathy, Genetic causes, Unknown
Cardiomyopathy DCMP - Differential ... Diagnosis Algorithm ... Sporadic Other secondary ... Dysthyroidism, Diabetes ... #Causes #cardiology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Diagnosis Renal ... Hypomagnesemia with secondary ... renal transplant, Diuretic ... #diagnosis #causes ... #nephrology #magnesium
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
- Differential ... Sodium >145 mmol/L High ... Osmotic diuresis (see ... 300 mmol/kg • Diabetes ... Hypernatremia #Nephrology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... heart failure • Diabetes ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes