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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Erythematosus #SLE ... #hematology #rheumatology ... #differential #diagnosis ... #causes
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... #Nephritis #SLE ... #Classification ... #Classes #differential ... #diagnosis #management
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... > 0.5 g/24 hr, Class ... , Class Ill or IV ... #Criteria #SLE ... Erythematosus #diagnosis
#Diagnosis #Cardiology #Cardiac #Heart #Tumors #Masses #Differential #Classification
#Diagnosis #Cardiology ... Heart #Tumors #Masses ... #Differential #Classification
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... Discontinuation of causal ... Erythematosus (SLE ... Positive in 60-80% of cases ... #rheumatology #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Coagulation disorders CAUSES ... Quantity: • Primary Causes ... • Secondary Causes ... Gardner-Diamond syndrome CAUSES
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... Erythematosus #Diagnosis
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... Inflammatory • Systemic Lupus ... Spherocytosis • Acquired causes ... #Algorithm #Causes ... #Hematology
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm
Nail Plate - Pitting
 • Psoriasis
 • Alopecia Areata
Nail
Primary Dermatologic ... - Differential Diagnosis ... Telangiectasia • SLE ... #Differential #Diagnosis ... #Algorithm #causes
The Aetiology of Ventricular Tachycardia (VT) in the Structurally Normal Heart and in Structural Heart Disease
#Tachycardia #Classification ... #Causes #Structural ... #Cardiology #Differential ... #Diagnosis