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diagnosis rheumatology vasculitis differential management manifestations clinical comparison complications cryoglobulinemia cryoglobulins dermpath dil lesions mucocutaneous oncology pathology pathophysiology semiology sweet
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Rare (SSA+ for cutaneous ... Discontinuation of causal ... rare), Topics for cutaneous-DIL ... Lupusreference #druginduced ... #lupus #sle #comparison
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... the context of cutaneous ... disease (10%) : SLE ... Vasculitis #dermpath #dermatology ... #semiology #signs
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... hair follicles -> causes ... #SLE #Mucocutaneous ... pathophysiology #diagnosis #signs
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... reactions, and vaso-occlusive ... purpura: strong sign ... vasculitis, and SLE ... #rheumatology #classification
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... Rare (SSA+ for cutaneous ... Discontinuation of causal ... rare), Topics for cutaneous-DIL ... Lupusreference #DrugInduced
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... reactions, and vaso-occlusive ... purpura: Strong sign ... of cutaneous leukocytoclastic ... tract, and often causes
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