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diagnosis rheumatology differential causes erythematosus pain systemic algorithm classification disease msk syndrome vasculitis workup activation approach bone clinical comparison criteria
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Malar rash • SLE ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... HIV, hepatitis, herpes ... Chronic = RA, SLE ... , psoriatic arthritis ... #rheumatology #
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
chickenpox) • Herpes ... shingles) • Herpes ... Bullous systemic lupus ... Vesiculobullous #SkinRash ... #dermatology #Differential
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
with temporal arteritis ... Inclusion Body ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... diagnosis #comparison #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Disease Vaso-occlusive ... dz difficult to see ... Osteomyelitis / Septic Arthritis ... diagnosis #causes #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... in at least 2 joints ... pericarditis • Hematologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... of hip (rare), Arthritis ... in small joints ... #SLE #systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Malignancy (e.g. hematologic ... : • Joint pain ... arthropathy • 90% joints ... vein thrombosis Hematologic
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Fever/Chills/Joint ... Chikungunya - Herpes ... - SLE - Behcet ... Effusions: - Hematologic ... Osteochondroma Hematologic
Subacute Cutaneous Lupus erythematosus (SCLE): Erythematous, warm, plaques in light exposed distribution (also on patient's neck),
Subacute Cutaneous Lupus ... Subacute Cutaneous Lupus ... Images #Clinical #Dermatology ... #SkinRash #Subaute ... #Cutaneous #Lupus
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