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diagnosis rheumatology differential causes erythematosus algorithm arthritis disease msk oncology syndrome systemic vasculitis workup activation approach bone classification clinical clues
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... HIV, hepatitis, herpes ... Chronic = RA, SLE ... #Joint #Pain #MSK
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Disease Vaso-occlusive ... dz difficult to see ... BrighamChiefs #Bone #Joint ... diagnosis #causes #hematology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
chickenpox) • Herpes ... shingles) • Herpes ... Bullous systemic lupus ... Vesiculobullous #SkinRash ... #dermatology #Differential
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... temporal arteritis Inclusion ... Anti-retrovirals, Gemcitabine Lupus ... Diffuse muscle pain ... uncommon 5-15% of lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... phenomenon (20%) Joints ... lesions Abdominal pain ... #SLE #systemic
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... and fingers, or pain ... children (pediatric SLE ... #diagnosis #sle
Subacute Cutaneous Lupus erythematosus (SCLE): Erythematous, warm, plaques in light exposed distribution (also on patient's neck),
Subacute Cutaneous Lupus ... Subacute Cutaneous Lupus ... Images #Clinical #Dermatology ... #SkinRash #Subaute ... #Cutaneous #Lupus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Malignancy (e.g. hematologic ... Arthritis: • Joint ... pain • Swan neck ... arthropathy • 90% joints
Oral Skin Ulcers - Differential Diagnosis Algorithm Single Ulcer: • Traumatic ulcer • Angular ulcer • Aphthous
Aphthous ulcer • Herpes ... stomatitis • Herpes ... Lichen planus • Lupus ... #Oral #mouth #SkinRash ... #dermatology #Differential
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