14 results
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
• Loose anagen syndrome ... - Secondary to Skin ... Disease • ... #dermatology #Differential ... #causes
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... hair follicles -> causes ... inflammation on skin ... pathophysiology #diagnosis #signs
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Capitis - Skin ... Disease: Discoid ... , Loose anagen syndrome ... Examination: • Signs ... Differential #Diagnosis #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... and permanent alopecia ... Seizures • Strokes Skin ... • Nonscarring alopecia
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Tanning • Adverse cutaneous ... • Addison's disease ... McCune Albright syndrome ... #dermatology #Differential ... #causes
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 - Infectious
- Secondary to Skin ... Disease • ... Discoid lupus erythematosus ... Focal #Localized #dermatology ... #causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... : • Vascular occlusion ... Kasabach-Merritt syndrome ... Associated - SLE ... #nonpalpable #dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... (SVC/IVC occlusion ... Oral aphthae : SLE ... • Arthritis: SLE ... diagnosis #management #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... such as systemic lupus ... reactions, and vaso-occlusive ... purpura: strong sign ... vasculitis, and SLE
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... Episcleritis Signs ... Causes: - Idiopathic ... - Lupus - Leukemia