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diagnosis rheumatology differential erythematosus hairloss oncology systemic vasculitis behcet causes classification complications diffuse disease focal hair hematology leukemia management manifestations
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin ... Disease: Discoid lupus ... , Loose anagen syndrome ... Examination: • Signs ... #Diagnosis #dermatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... inflammation on skin ... pathophysiology #diagnosis #signs ... #symptoms #complications
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Hair Loss (Alopecia ... Differential Diagnosis Algorithm ... • Loose anagen syndrome ... - Secondary to Skin ... #dermatology #Differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(75%), Weight loss ... Sjögrens (15%) Skin ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... arthritis, weight loss ... 3rd Decade Skin ... and permanent alopecia ... : • Symptoms limited
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
vasculitis) • Cutaneous ... disease (SVC/IVC occlusion ... Oral aphthae : SLE ... • Arthritis: SLE ... diagnosis #management #signs
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Episcleritis Signs ... and Symptoms: ... - Lupus - Leukemia ... #diagnosis #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
reactions, and vaso-occlusive ... Presentation - Systemic Symptoms ... Anorexia • Weight loss ... purpura: strong sign ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... reactions, and vaso-occlusive ... Anorexia • Weight loss ... purpura: Strong sign ... malaise, weight loss
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Fatigue, weight loss ... develop leukostasis syndrome ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... CLL -> Invade Skin
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