9 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... inflammation on skin ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... and permanent alopecia ... • Nonscarring alopecia ... : • Symptoms limited
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms ... Xeroderma (Dry skin ... #Pathophysiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... meningitis), MCC CNS symptoms ... disease (SVC/IVC occlusion ... Oral aphthae : SLE ... • Arthritis: SLE
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Episcleritis Signs and Symptoms ... symptoms by days ... - Lupus - Leukemia ... #diagnosis #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
such as systemic lupus ... reactions, and vaso-occlusive ... Presentation - Systemic Symptoms ... strong sign of cutaneous ... vasculitis, and SLE
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
weakness without skin ... Guillain-Barré syndrome ... GBS), systemic lupus ... erythematosus (SLE ... dermatomyositis, inclusion
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... reactions, and vaso-occlusive ... Presentation: Systemic Symptoms ... Strong sign of cutaneous ... • Progressive symptoms