39 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... permanent alopecia ... pain • Swan neck ... : • Symptoms limited
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
of Lumbar Spine and ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Capitis - Skin ... Disease: Discoid ... lupus erythematosus ... , Loose anagen syndrome ... Differential #Diagnosis #dermatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Demyelinating syndromes ... lesions Abdominal pain ... (20%) Renal disease ... erythematosus #signs #symptoms
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Irreversible-biopsy required • Lupus ... • Loose anagen syndrome ... - Secondary to Skin ... Disease • ... #dermatology #Differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Extra-articular and ... Associated with Joint ... Pain Eyes ... Scleroderma Thickened skin ... #pain #differential
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... Associated with skin ... #Systemic #Lupus ... #rheumatology #management
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... ), Sjogren's Syndrome ... : Lupus (SLE), Systemic ... Arthritis, Sjögren Syndrome
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... Photosensitivity, Alopecia ... Workup: - ANA ... : Chronic disease