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diagnosis rheumatology differential hematology management signs algorithm oncology causes classification erythematosus hairloss leukemia msk myopathy pathophysiology systemic activation agglutinin anemia
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... permanent alopecia ... pain • Swan neck ... : • Symptoms limited
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... lesions Abdominal pain ... (20%) Renal disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... vaso-occlusive ... Presentation - Systemic Symptoms ... LFT • ESR • ANA ... , and SLE) • Urinalysis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
of Lumbar Spine and ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Pain Eyes ... Vasculitis (e.g. ... Scleroderma Thickened skin ... #pain #differential
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin ... Disease: Discoid ... lupus erythematosus ... , Loose anagen syndrome ... Differential #Diagnosis #dermatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... inflammation on skin ... Livedo Reticularis, Vasculitis ... diagnosis #signs #symptoms
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Irreversible-biopsy required • Lupus ... • Loose anagen syndrome ... - Secondary to Skin ... Disease • ... #dermatology #Differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... surfaces of the joints ... burning sensation or pain ... • Goodpasture syndrome ... #Dermatologic
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