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diagnosis differential rheumatology algorithm causes hairloss hematology oncology signs symptoms syndrome classification cutaneous erythematosus focal management manifestations systemic behcet clinical
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... lesions • Discoid lupus ... Sarcoidosis #dermatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... inflammation on skin ... Livedo Reticularis, Vasculitis ... #SLE #Mucocutaneous
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin ... Disease: Discoid lupus ... : Lupus erythematosus ... Examine the entire skin ... Differential #Diagnosis #dermatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Hair Loss (Alopecia ... Irreversible-biopsy required • Lupus ... - Secondary to Skin ... • Discoid lupus ... #dermatology #Differential
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... the Skin - Differential ... Secondary: CTD: SLE ... Skin Findings: ... #skin #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... and permanent alopecia ... Seizures • Strokes Skin ... • Nonscarring alopecia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... : • Vascular occlusion ... Splenomegaly - CTD (SLE ... Associated - SLE ... #nonpalpable #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... inflammation Others: • Lupus ... such as systemic lupus ... reactions, and vaso-occlusive ... , and SLE) • Urinalysis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... #SLE #systemic
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... dermatomyositis, SLE ... leukocytoclastic vasculitis ... differential #diagnosis #dermatology ... oncology #clinical #skin
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