22 results
diagnosis rheumatology management clinical differential syndrome erythematosus classification hematology oncology rash signs symptoms acne acute algorithm ana anca antibody antineutrophil
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... ) • Systemic sclerosis ... ANCA-Associated Vasculitis ... vasculitis - MPO
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Abdominal pain (20%) Renal ... #SLE #systemic
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... Associated with skin ... severe disease Treatment ... #Lupus #Erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... lupus erythematosus ... C-ANCA) pattern: antibodies ... , and SLE) • Urinalysis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Seizures • Strokes Skin ... 1, SCL-70, RNP antibodies ... #Systemic #Lupus
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
resulting in a vasculitis ... which causes slowly ... ulceration of the skin ... a number of systemic ... #Dermatology #SkinRash
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Infection - Vasculitis ... (lupus, RA, Sjogren's ... cryoglobulins • Skin ... #dermatology #physicalexam
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... lupus erythematosus
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... , retinal, DVT,
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Vasculitis: • ... Adenocarcinoma Treatment
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