21 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Lupus Erythematosus ... #SLE #hematology ... differential #diagnosis ... #causes
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... (common causes ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Reaction with Eosinophilia ... and Systemic Signs ... medication (in this case ... Images #Clinical #Dermatology ... #Photo #UCSDH
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Reaction with Eosinophilia ... and Systemic Signs ... medication (in this case ... Images #Clinical #Dermatology ... #Legs #Photo #UCSDH
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... #lupus #Systemic
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... #SLE #systemic ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... months to years) Systemic ... • Immunologic Workup ... #diagnosis #management
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
lupus erythematosus ... in drug-induced SLE ... ANCA+ 60% • Eosinophilic ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Reaction with Eosinophilia ... and Systemic Signs ... medication (in this case ... Images #Clinical #Dermatology ... #Trunk #Photo #