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diagnosis differential rheumatology neurology erythematosus management symptoms vasculitis behcet causes cerebritis chronic classification cll cord disease hematology leukemia lymphocytic manifestations
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus (SLE ... Demyelinating Syndrome ... #SLE #CNS #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS ... Comorbid autoimmune disorders ... (Systemic lupus ... Manifestations #diagnosis #neurology ... #symptoms #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) • Endocrine disorders ... and CNS • Headache ... APLA/LAC: • Renal ... #Systemic #Lupus
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... pulmonary etc) • CNS ... -> PNS -> NMJ - ... Lack of UMN/LMN signs ... dystrophies Work
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... aneurysms Diagnosis: No ... Oral aphthae : SLE ... • Arthritis: SLE ... diagnosis #management #signs
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... • Many with no ... Physical Exam/Signs ... lymphoproliferative disorders ... Leukemia #diagnosis #workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Polyangiitis: - No ... inflammation Others: • Lupus ... lupus erythematosus ... purpura: strong sign ... vasculitis, and SLE
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
• Symptoms and signs ... Behcet disease - SLE ... , Scleroderma, Systemic ... MCTD, Sjogren syndrome ... differential #algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... diseases, such as SLE ... purpura: Strong sign ... polyangiitis • No ... chorioretinitis, CNS
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