18 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
process whereas secondary ... diseases • In secondary ... (PBC), or with systemic ... lupus erythematosus ... (SLE) Signs /
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... #SLE #systemic ... erythematosus #signs
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
inhibitors, hepatorenal syndrome ... Glomerulonephritides (GN) • Primary ... nephropathy • Secondary ... GNs: Due to systemic ... Post-infectious GN, Lupus
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm - Systemic ... BUN: • Chronic renal ... Myelodisplastic syndrome ... #secondary #systemic ... #generalized #dermatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... discoloration) • Chronic renal ... • Nephrotic syndrome ... #Secondary #dermatology
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Primary (Essential) (95%) - Onset between age
Primary and Secondary ... Diagnosis Algorithm Primary ... taken at home, work ... excess (Cushing syndrome ... Hyperthyroidism (mainly systolic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Diagnosis #Management #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... the context of primary ... Neuropsychiatric systemic ... APLA/LAC: • Renal ... #Systemic #Lupus
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Hypertension - Workup ... damage such as retinal ... bruit or signs ... Hypothyroidism, Primary
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
frequently affected systems ... some time, let’s see ... EPO-independent (primary ... up EPO levels Primary ... you’ll do a good workup