6 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... process whereas secondary ... lupus erythematosus ... (SLE) Signs / ... #Sjogrens #Syndrome
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... loss (50%) Eye: Sjögrens ... Demyelinating syndromes ... #SLE #systemic ... erythematosus #signs
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Classified among the secondary ... lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) •
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... dermatomyositis, Sjogren ... the context of primary ... Chronic B-cell activation ... #Systemic #Lupus
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Vaginal dryness • Primary ... other diseases • Secondary ... overlaps with RA, SLE ... enlargement Sjogren's
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... Types of HLH • Primary ... STX11, STXBP2 • Secondary ... Presentation • Common Signs ... Diagnosis #Management #Hematology