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diagnosis rheumatology differential hematology erythematosus sjogrens symptoms causes chronic classification cll cryofibrinogenemia hypertension indications leukemia lymphocytic management monoclonal paraproteinemias pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
process whereas secondary ... diseases • In secondary ... (PBC), or with systemic ... lupus erythematosus ... (SLE) Signs /
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... #SLE #systemic ... erythematosus #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... • Cogan Syndrome ... lupus erythematosus ... purpura: strong sign ... , and SLE) • Urinalysis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ANCA-associated vasculitis ... the context of primary ... APLA/LAC: • Renal ... #Systemic #Lupus
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Causes of Secondary ... Hypertension - Workup ... damage such as retinal ... Coarctation of aorta, Vasculitis ... Hypothyroidism, Primary
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Leukocytoclastic vasculitis ... - Lupus - Leukemia ... #diagnosis #dermatology ... #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... diseases, such as SLE ... purpura: Strong sign ... with GCA or as primary ... Rash, arthritis Primary
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... other diseases • Secondary ... overlaps with RA, SLE ... ) • Cutaneous vasculitis ... Vasculitis: •
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... ’s CLL Scoring system ... Leukemia #diagnosis #workup ... #oncology #hematology
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