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hematology differential rheumatology gammopathy significance syndrome algorithm behcet causes chronic classification clinical cll diffuse disease erythematosus lymphadenopathy lymphocytic management paraproteinemias
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... - Differential Diagnosis ... #Significance #MGUS ... #Differential #Diagnosis ... #hematology #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Lupus Erythematosus ... Lymphocytes) - Monoclonal ... Lymphadenopathy #LAD ... #Oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoantibodies: • WAIHA • CAD ... to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Significance (MGUS ... constitutional symptoms ... hyperCalcemia, Renal ... #Significance #hematology ... #diagnosis #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... activity • ↓ LAP ... #Hematology #Oncology ... #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... APLA/LAC: • Renal ... : • Symptoms limited ... Hodgkin lymphoma and leukemia ... #Systemic #Lupus
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... non-Hodgkin lymphoma SLL ... with no early symptoms ... ’s CLL Scoring system ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
development of skin symptoms ... ’s syndrome - Lupus ... Diagnosis: ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Oral aphthae : SLE ... tears, Ischemia, Leukemia ... • Arthritis: SLE ... refractory disease : monoclonal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... lupus erythematosus ... Symptoms (Sx) in ... retinopathy Lab ... vasculitis, and SLE
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