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diagnosis hematology rheumatology algorithm causes systemic activation autoantibodies classification criteria hemolytic high hyperkalemia macrophage management mas mimickers monoclonal naildisorders nonpalpable
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Hypersplenism • Secondary ... RA, SLE, PRV, Chronic ... Bleed • Hemolysis ... #Differential #
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... - SEROSITIS - RENAL ... ANEMIA - LEUKOPENIA ... #Lupus #Erythematosus
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Diseases: • Systemic lupus ... erythematosus ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... Lupusreference #SLE ... #Erythematosus
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... genotypes): SS, SC, SE ... #Anemia #Differential ... Diagnosis #Algorithm #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia ... : Drug induced SLE
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... Iron deficiency anemia ... discoloration) • Chronic renal ... #dermatology #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
anemia Indirect ... WBC count and differential ... the presence of renal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... - CTD (SLE)
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... erythematosus ... erythematosus [ ... SLE], AOSD) • Infection ... with leukopenia, anemia
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