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diagnosis rheumatology differential systemic classification activation eularacr gap globulin macrophage management mas monoclonal oncology paraproteinemias protein proteingap slicc symptoms syndrome
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Lupus Erythematosus ... - SEROSITIS - RENAL ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus ... pericarditis • Hematologic ... hemolysis • Renal ... #SLE #Systemic ... #Lupus #Erythematosus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: ... Abdominal pain (20%) Renal ... ) Blood (75%): Anemia ... #erythematosus # ... signs #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Malignancy (e.g. hematologic ... APLA/LAC: • Renal ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... , retinal, DVT, ... Paraproteinemias #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Histopathologic criteria ... Diagnosis #Management #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... erythematosus, ... purpura: strong sign ... vasculitis, and SLE ... • Urinalysis (Renal
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Gammopathy Include: • MGUS ... cancers, HCC, renal ... gastric tumors • Hematology ... differential #diagnosis #hematology
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