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Renal involvement in Systemic Lupus Erythematosus (SLE)

Dr. Laurent ARNAUD @Lupusreference

#Renal #lupus #nephritis #SLE #Systemic #Erythematosus #SLE
Renal involvement ... in Systemic Lupus ... Lupusreference #Renal ... #lupus #nephritis ... #management #treatment
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... Immunosuppression to treat non-renal ... SLE 4. ... to treat extra-renal ... #management #nephrology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... severe disease Treatment ... #Systemic #Lupus ... #rheumatology #management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... in 10 to 40% of SLE ... or 0.5 g/day → renal ... #treatment #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
post-hypothermia • ↓ Renal ... Excretion: - Renal ... reabsorption) Workup ... 15 suggests ↓ renal ... and Elimination (see
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
again we might see ... contribution of liver or renal ... 30mmHg) - Severe anemia ... deficiency - Renal ... lactate production Renal
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
❹ Call for MH treatment ... metoprolol Metabolic acidosis ... ); may require renal ... Checklist #Diagnosis #Management ... #Workup
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SJIA], systemic lupus ... erythematosus [SLE ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
syndrome (PRIS) - acidosis ... , bradycardia. renal ... drug, it causes amnesia ... result in lactic acidosis ... CriticalCare #diagnosis #management
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
ECF and ICF both work ... increased risk of renal ... content induces renal ... which reduces renal ... showing reduced renal