23 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal Involvement ... in Systemic Lupus ... #diseases #SLE ... #Systemic #Lupus ... venn #nephrology #nephritis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... nephritis, NPSLE ... Evolution: Chronic disease ... Lupusreference #druginduced ... #lupus #sle #comparison
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... SLE 4. ... for worsening disease ... SLE • Calcineurin ... #Membranous #Lupus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... nephritis, NPSLE ... • Immunologic Workup ... Positive in 60-80% of cases ... Evolution: Chronic disease
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... (nephrotic-range ... APLA/LAC: • Renal ... SSA can rule in SLE ... papillomavirus #SLE
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... approach to kidney disease ... with systemic lupus ... Non-LN Kidney Disease ... (5%) #Lupus
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
M DAMN SHARP - Lupus ... Arthritis R Renal ... Disease (Nephritis ... #IMDAMNSHARP #sle ... #systemic #lupus
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Chronic renal ... discoloration) • Nephrotic ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm #causes
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... • Primary GNs: Disease ... Due to systemic disease ... Post-infectious GN, Lupus ... Acute Interstitial Nephritis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... test, ANA (e.g., SLE ... bypass), LFT (liver disease ... #Workup #hematology