26 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... Demyelinating syndromes ... #SLE #systemic ... #diagnosis #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
lupus erythematosus ... (SLE) Signs / ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... (SLE), Systemic ... (SLE), Systemic ... , Interstitial Pulmonary ... #rheumatology #diagnosis
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Rhinitis - Allergic ... Lymphomas - Systemic ... Hypereosinophilic Syndrome ... #Causes #hematology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Lupus - with Systemic ... (SLE), should have ... other symptoms
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
(Skin and Mucosa ... arrest, Kounis syndrome ... anaphylaxis #signs #symptoms ... #diagnosis #criteria ... #allergy
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
symptoms by days ... Causes: - Idiopathic ... - Allergic contact ... - Lupus - Leukemia ... #diagnosis #dermatology
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
loss, malaise • Allergic ... Hypereosinophilic Syndrome ... loss; CV, CNS, skin ... Lung #Diseases #pulmonary ... #differential #diagnosis
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
a.k.a. extrinsic allergic ... Tissue Disease: • Systemic ... Polymyositis-dermatomyositis, Lupus ... Churg Strauss syndrome ... Diseases #ILD #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Differential Diagnosis ... : • Symptoms limited ... #Systemic #Lupus